Death of Khadija
Khadija died in 'Ramadan of the year 10 after the Prophethood', i.e., in November 619 CE. Muhammad later called this tenth year the 'Year of Sorrow', as his uncle and protector Abu Talib also died at this time. Khadija is said to have been about 65 years old at the time of her death. She was buried in Jannat al-Mu'alla cemetery, in Mecca, Saudi Arabia.
Another report from Muhammad bin Ishaq says that 'Abu Talib and Khadija bint Khuwaylid died in the same year. This was three years before the emigration of the Messenger of Allah (Muhammad) to Medina. Khadija was buried in al-Hajun. The Messenger of Allah buried her in her grave. She was 40 years old when the Messenger of Allah married her.
In the years immediately following Khadija's death, Muhammad faced persecution from opponents of his message and also from some who originally followed him but had now turned back. Hostile tribes ridiculed and stoned him. Muhammad migrated to Yathrib (Medina) after Khadija's death.